Cystitis

Responsible pathogen complex #

Cystitis represents more than a simple local irritation of the bladder lining. It reflects a persistent infectious burden affecting urinary epithelium, vascular integrity, and mucosal immunity. Multiple bacteria, sexually transmitted pathogens, and blood flukes contribute to chronic inflammatory signaling, tissue irritation, and impaired bladder stability.

Gardnerella vaginalis ovarian and genital tract infection

Associated with genital tract imbalance. Its presence alters mucosal defense mechanisms and promotes ascending microbial colonization toward the bladder.

Proteus mirabilis

A classic urinary pathogen. It produces enzymes and metabolic by‑products that irritate bladder mucosa and destabilize urinary tract pH, promoting recurrent inflammation.

Proteus vulgaris urinary tract pathogen

Contributes to persistent urinary irritation. Multiple frequency ranges reflect adaptive strain variability and recurrent colonization.

Salmonella species

Although primarily intestinal organisms, systemic spread and immune activation sustain inflammatory mediators that influence urinary tract tissues.

Campylobacter fetus smear and Campylobacter pyloridis

Contribute to systemic inflammatory signaling. Chronic microbial burden increases immune reactivity and mucosal vulnerability.

Chlamydia trachomatis

An intracellular pathogen capable of persistent infection. It sustains low‑grade inflammation within urogenital tissues and promotes recurrent cystitis.

Trichomonas vaginalis

Protozoan infection disrupts mucosal integrity and facilitates bacterial co‑infection, reinforcing inflammatory cycles.

Escherichia coli (E. coli)

A dominant urinary pathogen. Its adhesion to bladder epithelium and toxin production drive acute and chronic cystitis.

Schistosoma haematobium and Schistosoma mansoni

Blood flukes that impair vascular stability and cause chronic inflammatory irritation of urinary tissues, especially in endemic exposure contexts.

Neisseria gonorrhea

Mucosal pathogen that promotes ascending infection and persistent inflammatory stress within the urinary tract.

Treponema pallidum

Systemic spirochete capable of vascular and tissue involvement, contributing to chronic inflammatory burden.

Integrated impact: Bacterial pathogens dominate acute bladder irritation, while intracellular organisms and protozoa sustain chronic inflammatory signaling. Parasitic involvement compromises vascular integrity and mucosal resilience. Together, this pathogen complex maintains epithelial irritation, immune activation, and recurrent urinary inflammation characteristic of cystitis.

Frequency session table #

Pathogen	Use freq. (kHz)	Freq. low–high (kHz)
Gardnerella vaginalis ovarian and genital tract infection	340	338–342.55
Proteus mirabilis	324	320.55–326
Proteus mirabilis (2nd freq.)	349	345.95–352.1
Proteus vulgaris urinary tract pathogen	413	408.75–416.45
Proteus vulgaris urinary tract pathogen (2nd freq.)	336	333.75–339.15
Proteus vulgaris urinary tract pathogen (3rd freq.)	328	327.2–329.5
Salmonella enteriditis intestinal infection	329	329–329
Salmonella paratyphi	368	365.05–370.1
Salmonella typhimurium food poisoning, nervousness, apathy	385	382.3–386.55
Salmonella typhimurium food poisoning, nervousness, apathy (2nd freq.)	355	—
Salmonella typhimurium food poisoning, nervousness, apathy (3rd freq.)	386	—
Salmonella typhimurium food poisoning, nervousness, apathy (4th freq.)	390	—
Campylobacter fetus smear	368	365.3–370.6
Campylobacter fetus smear (2nd freq.)	355	352–357.2
Chlamydia trachomatis	381	379.7–383.95
Trichomonas vaginalis	381	378–383.6
Escherichia coli (E. coli) intestinal bacterium	356	356–356
Escherichia coli (E. coli) intestinal bacterium (2nd freq.)	393	356–356
Schistosoma haematobium	473	473–473
Schistosoma mansoni	353	353–353
Neisseria gonorrhea causes gonorrhea	334	333.85–336.5
Treponema pallidum causes syphilis	347	346.85–347.4